Purified Anti-Human CD178 (Fas ligand) (NOK-1)
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between ≥ ≥ ≥ CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
| Name | Purified Anti-Human CD178 (Fas ligand) (NOK-1) |
|---|---|
| Cat. No. | 70-9919 |
| Alternative Names | CD95L, Fas ligand, FasL |
| Gene ID | 356 |
| Clone | NOK-1 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | Purified |
| Application | Flow Cytometry, IP |
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Purified Anti-Human CD178 (Fas ligand) (NOK-1)
Purified Anti-Human CD178 (Fas ligand) (NOK-1)
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between ≥ ≥ ≥ CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
| Name | Purified Anti-Human CD178 (Fas ligand) (NOK-1) |
|---|---|
| Cat. No. | 70-9919 |
| Alternative Names | CD95L, Fas ligand, FasL |
| Gene ID | 356 |
| Clone | NOK-1 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | Purified |
| Application | Flow Cytometry, IP |
Original: $122.00
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$36.60Product Information
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Description
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between ≥ ≥ ≥ CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
| Name | Purified Anti-Human CD178 (Fas ligand) (NOK-1) |
|---|---|
| Cat. No. | 70-9919 |
| Alternative Names | CD95L, Fas ligand, FasL |
| Gene ID | 356 |
| Clone | NOK-1 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Format | Purified |
| Application | Flow Cytometry, IP |
