Integrin beta 7 Monoclonal Antibody (FIB504), Biotin, eBioscience
PRODUCT DETAILS
Host: Rat
Isotype: IgG2a, kappa
Clonality: Monoclonal
Clone: FIB504
Format: Biotin
Reactivity: Hu, Ms
Application: Flow Cytometry
Tested Dilution: 0.125 µg/test
Concentration: 0.5 mg/mL
Storage: 4°C, do not freeze
Formulation: PBS with 0.09% sodium azide; pH 7.2
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta7. Integrin beta7 is a 130 kD glycoprotein which associates with integrin alpha4 (CD49d) to form the alpha4beta7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alphaE (CD103) to form the alphaEbeta7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha4beta7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alphaEbeta7 is E-cadherin (CD324). Integrin beta7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Applications Reported: This FIB504 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This FIB504 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Filtration: 0.2 µm post-manufacturing filtered.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Integrin beta 7 Monoclonal Antibody (FIB504), Biotin, eBioscience
Integrin beta 7 Monoclonal Antibody (FIB504), Biotin, eBioscience
PRODUCT DETAILS
Host: Rat
Isotype: IgG2a, kappa
Clonality: Monoclonal
Clone: FIB504
Format: Biotin
Reactivity: Hu, Ms
Application: Flow Cytometry
Tested Dilution: 0.125 µg/test
Concentration: 0.5 mg/mL
Storage: 4°C, do not freeze
Formulation: PBS with 0.09% sodium azide; pH 7.2
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta7. Integrin beta7 is a 130 kD glycoprotein which associates with integrin alpha4 (CD49d) to form the alpha4beta7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alphaE (CD103) to form the alphaEbeta7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha4beta7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alphaEbeta7 is E-cadherin (CD324). Integrin beta7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Applications Reported: This FIB504 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This FIB504 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Filtration: 0.2 µm post-manufacturing filtered.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Original: $277.00
-70%$277.00
$83.10Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
PRODUCT DETAILS
Host: Rat
Isotype: IgG2a, kappa
Clonality: Monoclonal
Clone: FIB504
Format: Biotin
Reactivity: Hu, Ms
Application: Flow Cytometry
Tested Dilution: 0.125 µg/test
Concentration: 0.5 mg/mL
Storage: 4°C, do not freeze
Formulation: PBS with 0.09% sodium azide; pH 7.2
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta7. Integrin beta7 is a 130 kD glycoprotein which associates with integrin alpha4 (CD49d) to form the alpha4beta7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alphaE (CD103) to form the alphaEbeta7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha4beta7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alphaEbeta7 is E-cadherin (CD324). Integrin beta7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Applications Reported: This FIB504 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This FIB504 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Filtration: 0.2 µm post-manufacturing filtered.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
