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IL-33R (ST2) Monoclonal Antibody (RMST2-33), PE, eBioscience

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IL-33R (ST2) Monoclonal Antibody (RMST2-33), PE, eBioscience

IL-33R (ST2) Monoclonal Antibody (RMST2-33), PE, eBioscience

PRODUCT DETAILS

Host: Rat

Isotype: IgG2b, kappa

Clonality: Monoclonal

Clone: RMST2-33

Format: PE

Reactivity: Ms

Application: Flow Cytometry

Tested Dilution: Assay-Dependent

Concentration: 0.2 mg/mL

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: The RMST2-33 monoclonal antibody reacts with mouse ST2, also known as IL-33R or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extracellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. IL-33/ST2 interaction has also been shown to be atheroprotective.

RMST2-33 has been reported to bind and activate ST2 in in vitro assays.

Applications Reported: This RMST2-33 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This RMST2-33 antibody has been tested by flow cytometric analysis of mouse bone marrow-derived mast cells.

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
$424.00
IL-33R (ST2) Monoclonal Antibody (RMST2-33), PE, eBioscience
$424.00

Product Information

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Description

PRODUCT DETAILS

Host: Rat

Isotype: IgG2b, kappa

Clonality: Monoclonal

Clone: RMST2-33

Format: PE

Reactivity: Ms

Application: Flow Cytometry

Tested Dilution: Assay-Dependent

Concentration: 0.2 mg/mL

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: The RMST2-33 monoclonal antibody reacts with mouse ST2, also known as IL-33R or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extracellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. IL-33/ST2 interaction has also been shown to be atheroprotective.

RMST2-33 has been reported to bind and activate ST2 in in vitro assays.

Applications Reported: This RMST2-33 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This RMST2-33 antibody has been tested by flow cytometric analysis of mouse bone marrow-derived mast cells.

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
IL-33R (ST2) Monoclonal Antibody (RMST2-33), PE, eBioscience | Cytek Biosciences