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CD26 Monoclonal Antibody (H194-112 (H194-112.12.4.4.5)), PerCP-Cyanine5.5, eBioscience

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CD26 Monoclonal Antibody (H194-112 (H194-112.12.4.4.5)), PerCP-Cyanine5.5, eBioscience

CD26 Monoclonal Antibody (H194-112 (H194-112.12.4.4.5)), PerCP-Cyanine5.5, eBioscience

PRODUCT DETAILS

Host: Rat

Isotype: IgG2a, kappa

Clonality: Monoclonal

Clone: H194-112 (H194-112.12.4.4.5)

Format: PerCP-Cyanine5.5

Reactivity: Ms

Application: Flow Cytometry

Tested Dilution: 1 µg/test

Concentration: 0.2 mg/mL

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: The monoclonal antibody H194-112 recognizes mouse CD26, a thymocyte-activating molecule (THAM). CD26 is a surface expressed and soluble ectoenzyme (dipeptidyl peptidase IV) that cleaves dipeptides from the amino terminus of proteins. In particular CD26 has been shown to cleave CXCL12, CCL22, neuropeptide Y and glucagon. CD26 is involved in adhesion, apoptosis, disease regulation, and engraftment. Expression is regulated during thymic development at the messenger RNA level. Additionally, CD26 protein is found on thymocytes, a percentage of resting B cells, stimulated B cells, NK cells and a percentage of resting and activated T cells and other epithelial cell types. On human cells more CD26 protein is found on Th2 cells. Functional CD26 is expressed on Sca-1+c-Kit+lin- cells. This expression has been shown to correlate with mobilization of progenitor cells. Inhibition of CD26 activity through a variety of compounds enhances allogenic stem cell homing and engraftment.

This antibody is reported to have activating function.

Applications Reported: This H194-112 (H194-112.12.4.4.5) antibody has been reported for use in flow cytometric analysis.

Applications Tested: This H194-112 (H194-112.12.4.4.5) antibody has been tested by flow cytometric analysis of mouse splenocytes or thymocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
$124.20

Original: $414.00

-70%
CD26 Monoclonal Antibody (H194-112 (H194-112.12.4.4.5)), PerCP-Cyanine5.5, eBioscience

$414.00

$124.20

Product Information

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Description

PRODUCT DETAILS

Host: Rat

Isotype: IgG2a, kappa

Clonality: Monoclonal

Clone: H194-112 (H194-112.12.4.4.5)

Format: PerCP-Cyanine5.5

Reactivity: Ms

Application: Flow Cytometry

Tested Dilution: 1 µg/test

Concentration: 0.2 mg/mL

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: The monoclonal antibody H194-112 recognizes mouse CD26, a thymocyte-activating molecule (THAM). CD26 is a surface expressed and soluble ectoenzyme (dipeptidyl peptidase IV) that cleaves dipeptides from the amino terminus of proteins. In particular CD26 has been shown to cleave CXCL12, CCL22, neuropeptide Y and glucagon. CD26 is involved in adhesion, apoptosis, disease regulation, and engraftment. Expression is regulated during thymic development at the messenger RNA level. Additionally, CD26 protein is found on thymocytes, a percentage of resting B cells, stimulated B cells, NK cells and a percentage of resting and activated T cells and other epithelial cell types. On human cells more CD26 protein is found on Th2 cells. Functional CD26 is expressed on Sca-1+c-Kit+lin- cells. This expression has been shown to correlate with mobilization of progenitor cells. Inhibition of CD26 activity through a variety of compounds enhances allogenic stem cell homing and engraftment.

This antibody is reported to have activating function.

Applications Reported: This H194-112 (H194-112.12.4.4.5) antibody has been reported for use in flow cytometric analysis.

Applications Tested: This H194-112 (H194-112.12.4.4.5) antibody has been tested by flow cytometric analysis of mouse splenocytes or thymocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD26 Monoclonal Antibody (H194-112 (H194-112.12.4.4.5)), PerCP-Cyanine5.5, eBioscience | Cytek Biosciences