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CD169 (Siglec-1) Monoclonal Antibody (7-239), Alexa Fluor 488, eBioscience

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CD169 (Siglec-1) Monoclonal Antibody (7-239), Alexa Fluor 488, eBioscience

CD169 (Siglec-1) Monoclonal Antibody (7-239), Alexa Fluor 488, eBioscience

PRODUCT DETAILS

Host: Mouse

Isotype: IgG1, kappa

Clonality: Monoclonal

Clone: 7-239

Format: Alexa Fluor 488

Reactivity: Hu

Application: Flow Cytometry

Tested Dilution: 5 µL (0.125 µg)/test

Concentration: 5 μL/Test

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.

This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.

Applications Reported: This 7-239 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 7-239 antibody has been pre-diluted and tested by flow cytometric analysis of cultured normal human peripheral blood cells. This may be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
$120.60

Original: $402.00

-70%
CD169 (Siglec-1) Monoclonal Antibody (7-239), Alexa Fluor 488, eBioscience

$402.00

$120.60

Product Information

Shipping & Returns

Description

PRODUCT DETAILS

Host: Mouse

Isotype: IgG1, kappa

Clonality: Monoclonal

Clone: 7-239

Format: Alexa Fluor 488

Reactivity: Hu

Application: Flow Cytometry

Tested Dilution: 5 µL (0.125 µg)/test

Concentration: 5 μL/Test

Storage: 4°C, store in dark, DO NOT FREEZE!

Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2

Purification: Affinity chromatography

Data Sheet: TDS


Specific Information

Description: This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.

This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.

Applications Reported: This 7-239 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 7-239 antibody has been pre-diluted and tested by flow cytometric analysis of cultured normal human peripheral blood cells. This may be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

 

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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