CD102 (ICAM-2) Monoclonal Antibody (CBR-IC2/2), Biotin, eBioscience
PRODUCT DETAILS
Host: Mouse
Isotype: IgG2a
Clonality: Monoclonal
Clone: CBR-IC2/2
Format: Biotin
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 10 μL/Test
Storage: 2-8°C
Formulation: TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: BMS109 does not cross react with mouse.
Intercellular Adhesion Molecule-2 (ICAM-2) is a 60 kDa surface glycoprotein that promotes adhesion between immune cells and the vascular endothelium. ICAM-2 is a member of the Ig-superfamily with two immunoglobulin-like extracellular domains. ICAM-2 is much more closely related to the two N-terminal domains of ICAM-1 (34% identity) than either ICAM-1 or ICAM-2 is to other members of the Ig-superfamily, demonstrating the existence of a subfamily of Ig-like ligands that bind the same integrin receptor. ICAM-2 is broadly distributed on hematopoietic cells. On resting lymphocytes, the ICAM-2 expression is several-fold higher than that seen with ICAM-1, while monocytes express equivalent levels of ICAM-1 and ICAM-2. In contrast to ICAM-1, neutrophils stain negative for ICAM-2. Just little or no ICAM-2 staining can be demonstrated on other cell lines, the sole exception being resting vascular endothelial cells, which possess high levels of ICAM-2, and small clusters of cells in lymphoid tissue germinal centres.
ICAM-2 expression is unaffected by a variety of inflammatory cytokines.
Applications Tested: Flow Cytometry.
Purity: >95%.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
CD102 (ICAM-2) Monoclonal Antibody (CBR-IC2/2), Biotin, eBioscience
CD102 (ICAM-2) Monoclonal Antibody (CBR-IC2/2), Biotin, eBioscience
PRODUCT DETAILS
Host: Mouse
Isotype: IgG2a
Clonality: Monoclonal
Clone: CBR-IC2/2
Format: Biotin
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 10 μL/Test
Storage: 2-8°C
Formulation: TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: BMS109 does not cross react with mouse.
Intercellular Adhesion Molecule-2 (ICAM-2) is a 60 kDa surface glycoprotein that promotes adhesion between immune cells and the vascular endothelium. ICAM-2 is a member of the Ig-superfamily with two immunoglobulin-like extracellular domains. ICAM-2 is much more closely related to the two N-terminal domains of ICAM-1 (34% identity) than either ICAM-1 or ICAM-2 is to other members of the Ig-superfamily, demonstrating the existence of a subfamily of Ig-like ligands that bind the same integrin receptor. ICAM-2 is broadly distributed on hematopoietic cells. On resting lymphocytes, the ICAM-2 expression is several-fold higher than that seen with ICAM-1, while monocytes express equivalent levels of ICAM-1 and ICAM-2. In contrast to ICAM-1, neutrophils stain negative for ICAM-2. Just little or no ICAM-2 staining can be demonstrated on other cell lines, the sole exception being resting vascular endothelial cells, which possess high levels of ICAM-2, and small clusters of cells in lymphoid tissue germinal centres.
ICAM-2 expression is unaffected by a variety of inflammatory cytokines.
Applications Tested: Flow Cytometry.
Purity: >95%.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Original: $312.00
-70%$312.00
$93.60Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
PRODUCT DETAILS
Host: Mouse
Isotype: IgG2a
Clonality: Monoclonal
Clone: CBR-IC2/2
Format: Biotin
Reactivity: Hu
Application: Flow Cytometry
Tested Dilution: Assay-Dependent
Concentration: 10 μL/Test
Storage: 2-8°C
Formulation: TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Purification: Affinity chromatography
Data Sheet: TDS
Specific Information
Description: BMS109 does not cross react with mouse.
Intercellular Adhesion Molecule-2 (ICAM-2) is a 60 kDa surface glycoprotein that promotes adhesion between immune cells and the vascular endothelium. ICAM-2 is a member of the Ig-superfamily with two immunoglobulin-like extracellular domains. ICAM-2 is much more closely related to the two N-terminal domains of ICAM-1 (34% identity) than either ICAM-1 or ICAM-2 is to other members of the Ig-superfamily, demonstrating the existence of a subfamily of Ig-like ligands that bind the same integrin receptor. ICAM-2 is broadly distributed on hematopoietic cells. On resting lymphocytes, the ICAM-2 expression is several-fold higher than that seen with ICAM-1, while monocytes express equivalent levels of ICAM-1 and ICAM-2. In contrast to ICAM-1, neutrophils stain negative for ICAM-2. Just little or no ICAM-2 staining can be demonstrated on other cell lines, the sole exception being resting vascular endothelial cells, which possess high levels of ICAM-2, and small clusters of cells in lymphoid tissue germinal centres.
ICAM-2 expression is unaffected by a variety of inflammatory cytokines.
Applications Tested: Flow Cytometry.
Purity: >95%.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
