Alexa Fluor® 488 anti-human/mouse/rat CD278 (ICOS)
ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development.
PRODUCT DETAILS
Clone: C398.4A
Antibody Type: Monoclonal
Reactivity: Human, Mouse, Rat
Format: Alexa Fluor 488
Host: Armenian Hamster
Isotype: IgG
Applications: FC - Quality tested SB - Reported in the literature, not verified in house
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
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Alexa Fluor® 488 anti-human/mouse/rat CD278 (ICOS)
Alexa Fluor® 488 anti-human/mouse/rat CD278 (ICOS)
ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development.
PRODUCT DETAILS
Clone: C398.4A
Antibody Type: Monoclonal
Reactivity: Human, Mouse, Rat
Format: Alexa Fluor 488
Host: Armenian Hamster
Isotype: IgG
Applications: FC - Quality tested SB - Reported in the literature, not verified in house
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
Original: $251.00
-70%$251.00
$75.30Product Information
Product Information
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Description
ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development.
PRODUCT DETAILS
Clone: C398.4A
Antibody Type: Monoclonal
Reactivity: Human, Mouse, Rat
Format: Alexa Fluor 488
Host: Armenian Hamster
Isotype: IgG
Applications: FC - Quality tested SB - Reported in the literature, not verified in house
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
